GoldenHour515 has recently released results of a survey on PSSD patients. I did a quick and dirty analysis where I tried to line up the symptoms against other patient surveys of Long COVID and post-vax.
- Lambert et al. Long COVID survey
- PVS Germany (data for females only, I didn’t spend time pooling female+male together) - English translation
- GoldeHour515 - see Reddit - Dive into anything
See the Google Sheet for the data in spreadsheet format: Symptom comparison (public for sharing version, fixed) - Google Sheets
You can see that there are overlapping symptoms like brain fog, fatigue, tinnitus, dizziness, etc. Some of the symptoms probably don’t overlap that heavily. PSSD by definition requires the person to have sexual dysfunction (similar to how ME/CFS requires PEM for a diagnosis), so I would expect sexual symptoms to be much lower in LC and post-vax symptoms. (However, nobody bothers to survey those sexual symptoms or to ask about anhedonia.)
PLRC survey data shows sexual dysfunction at 14.6% for cis men and 8% for cis women.
The PSSD survey was 70% male while most Long COVID surveys are somewhere around 70% female. So it’s interesting that the situation is flipped with PSSD leaning heavily male. The u/Bubzoluck survey also found around 2/3rds male for PSSD.
PSSD might be interesting because it’s a well-defined chronic illness where we know that the trigger is a specific drug. (For some reason, a small minority develops PSSD when they restart their SSRI.)
That you can develop chronic illness from a pharmaceutical is interesting because it suggests that there are multiple pathways to a Long COVID-esque illness: SSRIs, finasteride, the SARS-CoV-2 virus, COVID vaccines, and other vaccines may all be triggers for chronic illness. This is not a new idea, as John Chia has written about the various causes of ME/CFS (e.g. vaccines) including mold.
One commonality is the spike protein, but we know that spike protein cannot explain pre-pandemic chronic illness such as PSSD and ME/CFS. Another common denominator is that all of these things may activate the immune system and/or affect the body’s microbiome. SSRIs have some antimicrobial properties.
One angle for research is to figure out PSSD first as a stepping stone to figure out more complicated chronic illnesses.
The PSSD sufferers try some treatments that long haulers aren’t trying. Here’s a compilation of 100+ success stories: Hormones, dopamine agonists (e.g. adderall), and psychedelics are some of the popular, unusual treatments tried.
I am not recommending those treatments. Please be careful with anecdotes as some of them may be unreliable. Some of the treatments discussed are controlled substances so don’t blindly buy them off the Internet and get into trouble with the law.