My anecdote
Tilorone (1 pill/week) shifted my sleep cycle later. Taking artemisinin on top of tilorone shifted it back to a more normal sleep cycle. I can go to sleep at between 11-12PM.
It may help my irregular heartbeat slightly but I’m not 100% sure. I still have an irregular heartbeat despite tilorone helping a little.
This drug did less for me than ivermectin and black seed oil (from Nigella Sativa).